2'-O- and 3'-O- pyrimidine aminotether-containing oligonucleotides: Synthesis and conjugation chemistry

Article abstract of DOI:10.1016/0040-4039(95)00596-5

Nucleoside synthons carrying an aminohexyl moiety tethered at the 2'-O- or 3'-O- positions of uridine have been synthesized and incorporated into oligonucleotides. The aminohexyl tether was used to conjugate functionalities such as intercalators, nucleic