Protection of ψ(CH2NH) peptide bond with 2,4-dimethoxybenzyl group in solid-phase peptide synthesis

DOI: 10.1248/cpb.45.13

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 13 - 17 (1997)

Update date:2022-08-11

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Authors:

Sasaki, Yusuke

Abe, Junko

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Article abstract of DOI:10.1248/cpb.45.13

The reductive alkylation of a resin-bound amine by the Boc-amino aldehyde/NaBH₃CN method is accompanied with undesirable double alkylation at Xaaψ(CH₂NH)Gly sequences. To prevent the double alkylation, the utility of the 2,4-dimethox

Full text of DOI:10.1248/cpb.45.13

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