Steroids p. 255 - 266 (1983)
Update date:2022-08-16
Topics:
Watson, T. G.
Hosking, M.
Herz, J. E.
Torres, J. V.
Muller, J.
et al.
The synthesis of eighteen esters of norethisterone (17α-ethynyl-17β-hydroxyestr-4-en-3-one) is described.These all possess some form of α- and/or β-substitution in the ester side-chain.The work was undertaken in order to evaluate any long-acting fertility control effect intrinsic in such compounds.A pentamethyl disiloxy ether was also included in the group of substances prepared for testing because of its similar substitution pattern.
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