Tetrahedron Letters p. 4463 - 4466 (1996)
Update date:2022-08-17
Topics:
Zhao, Shu-Hai
Miller, Aubry K.
Berger, Jacob
Flippin, Lee A.
A series of arylpiperazines were synthesized in moderate to good yields by palladium-catalyzed coupling reaction of aryl halides with unprotected piperazines. Very high regioselectivities were observed when using 2-methyl or 2,6-dimethylpiperazine.
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Doi:10.1016/0301-0104(88)87140-4
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