Synthesis of vinca alkaloids and related compounds LX. A simple transformation of apovincamine into vincamine

DOI: 10.1016/S0040-4020(01)81593-3

Source and publish data:

Tetrahedron p. 4999 - 5008 (1992)

Update date:2022-08-29

Topics:

Authors:

Moldvai, Istvan

Szantay Jr., Csaba

Rissanen, Kari

Szantay, Csaba

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Article abstract of DOI:10.1016/S0040-4020(01)81593-3

The 15α-chloro-vincamine derivative 2 was prepared and proved to be key intermediate of a two-step transformation of apovincamine into vincamine. The structure of 2 was established via detailed NMR and X-ray investigations.

Full text of DOI:10.1016/S0040-4020(01)81593-3

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