Tetrahedron Letters p. 829 - 832 (1995)
Update date:2022-08-11
Topics:
Torok, Daniel S.
Ziffer, Herman
11-Azaartemisinin was prepared in 45% yield in a one pot, two-step sequence from the reaction of artemisinin with excess ammonia followed by acid treatment. Analogous reactions of artemisinin with primary alkylamines gave N-alkylazaartemisinins in similar yields.
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