Exo-Diastereoselective 1,3-Dipolar Cycloadditions of Azomethine Ylides to (2R)-3-Benzoyl-4-methylene-2-phenyloxazolidin-5-one

DOI: 10.1016/0040-4039(95)00294-M

Source and publish data:

Tetrahedron Letters p. 2511 - 2514 (1995)

Update date:2022-08-22

Topics:

Authors:

Pyne, Stephen G.

Safei-G., Javad

Koller, Fiona

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Article abstract of DOI:10.1016/0040-4039(95)00294-M

Exo-diastereoselective 1,3-dipolar cycloadditions of azomethine ylides derived from α-amino acid esters to (2R)-benzoyl-4-methylene-2-phenyloxazolidin-5-one (1) are reported.The cycloaddition products are conveniently converted to polyfunctional prolines in high enantiomeric purity.

Full text of DOI:10.1016/0040-4039(95)00294-M

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