Archiv der Pharmazie p. 751 - 755 (1980)
Update date:2022-08-17
Topics:
Reisch, Johannes
Mester, Iuliu
The reaction of 4-hydroxy-2-quinolone (1a) with methyl iodide/potassium hydroxide in boiling acetone gave a mixture of 1-methyl-4-methoxy-2-quinolone (1d), 1,3-dimethyl-4-methoxy-2-quinolone (1e), and 1,3,3-trimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinoline (2).As by-product 2,4-dimethoxyquinoline (3) was identified.Under the same conditions 4-methoxy-2-quinolone (1c) yielded 1d, 1e, 2 and 3, while 1-methyl-4-hydroxy-2-quinolone (1b) gave 1d, 1e and 2.
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Doi:10.1021/jo048312y
(2005)Doi:10.1007/BF01530256
(1910)Doi:10.1021/acs.chemmater.8b05237
(2019)Doi:10.1039/tf9363200336
()Doi:10.1016/j.jorganchem.2019.04.019
(2019)Doi:10.1039/d0ob01623c
(2020)
