Convergent total synthesis of epolactaene: Application of bridgehead oxiranyl anion strategy

Article abstract of DOI:10.1016/S0040-4039(99)01512-9

Total synthesis of (+)-epolactaene was accomplished by a convergent approach utilizing the fluoride anion-catalyzed aldol-type reaction of (-)-α-trimethylsilylangelica lactone epoxide with tetraene aldehyde as a key reaction.