Analytical Chemistry p. 2292 - 2295 (1995)
Update date:2022-08-11
Topics:
Egekeze, John O.
Danielski, Michael C.
Grinberg, Nelu
Smith, George B.
Sidler, Daniel R.
Perpall, Holly J.
Bicker, Gary R.
Tway, Patricia C.
The inherent instability of active esters provides a chromatographic challenge. A normal phase HPLC gradient was developed using nonprotic solvents and a diol stationary phase to determine the impurity profile of a mesylate which, under protic conditions,
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