Versatile approach to the synthesis of globoside glycosphingolipids synthesis of sialyl-galactosyl-globoside

Article abstract of DOI:10.1016/0040-4039(95)00771-4

Sialyl-galactosyl-globoside (SGG, 1), carrying the SSEA-4 antigen, is synthesized from readily available, versatile building blocks 2-7 in a convergent manner. Thus, appropriately protected tetra- and pentasaccharides 15 and 17 are generated, which constitute valuable intermediates for the synthesis of various other members of the globo-series of glycosphingolipids.