1,2-Fused pyrimidines VII. 3-(dialkylamino)-1H-pyrimido[1,2-a]quinolin-1-ones and 2-(dialkylamino)-4H-pyrimido[2,1-a]isoquinolin-4-ones as antiplatelet compounds

Article abstract of DOI:10.1016/0223-5234(96)88206-7

A number of 3-(dialkylamino)-1H-pyrimido[1,2-a]quinolin-1-ones 3 and 2-(dialkylamino)-4H-pyrimido[2,1-a]isoquinolin-4-ones 4 were prepared by treating the corresponding chloro derivatives with an excess of dialkylamines. The highest in vitro antiplatelet