Synthesis of 2-hydroxypyrido[2,3-a]carbazoles and 2-hydroxypyrimido[4,5- a]carbazoles from 1-hydroxycarbazoles

Article abstract of DOI:10.3987/com-99-8587

Gattermann reaction on substituted 1-hydroxycarbazoles (4a-d) afforded substituted 1-hydroxycarbazole-2-carbaldehydes (5a-d) from which synthesis of either 2-hydroxypyrido[2,3-a]carbazoles (7a-d) via Perkin reaction or 2- hydroxypyrimido[4,5-a]carbazoles (8a-d) via condensation with urea could be achieved.