Journal of the Chemical Society. Perkin transactions I p. 2103 - 2110 (1996)
Update date:2022-08-03
Topics:
Spivey, Alan C.
Frampton, Christopher S.
Battersby, Alan R.
A new two step procedure is developed for the half-reduction of lactams to cyclic imines and enamines. N-Nitrosation using dinitrogen tetroxide furnishes N-nitroso lactams, which undergo chemoselective 1,2-reduction to N-nitroso carbinolamines? by one equivalent of hydride delivered from lithium triethylborohydride. The nitroso group is cleaved in a novel way using samarium(II) iodide and dehydration then generates the corresponding imine (which may tautomerise to the isomeric enamine). The reduction can be performed in the presence of esters and has proved efficient for the preparation of 2H-pyrroles (pyrrolenines) and 1H-pyrroles relevant to the study of tetrapyrrole biosynthesis.
View MoreGuangzhou Flower's Song Fine Chemical CO,. Ltd
Contact:+86-20-87475199
Address:No.12, Fenghuang 3 Road, Jiulong Industrial Park, Luogang District, Guangzhou. China
Hunan Haili Chemical Industry Co.,Ltd.
Contact:+86-731-85521860
Address:No.251, 2nd Section, Furong Road, Changsha,Hunan,China
Contact:86-15588110016
Address:LINYI CITY,SHANDONG PROVINCE,CHINA
Weifang Adde Economic And Trade Co.,LTD.
Contact:86-536-8885548
Address:Room 1402,Wanda Plaza B Block,No.958,Yuanfei Road,Kuiwen District
Nantong Auxin Electronic Technology Co., LTD
Contact:86-513-88760026
Address:NO.5-1, Aoxin Road, Haian Hi-tech Development Zone, Jiangsu Province, China
Doi:10.1016/0957-4166(95)00204-3
(1995)Doi:10.1080/00397919508011482
(1995)Doi:10.1515/znb-1998-0208
(1998)Doi:10.3390/90400256
(2004)Doi:10.1007/BF00905763
()Doi:10.1021/jm9707479
(1998)
