Journal of the Chemical Society. Perkin transactions I p. 2103 - 2110 (1996)
Update date:2022-08-03
Topics:
Spivey, Alan C.
Frampton, Christopher S.
Battersby, Alan R.
A new two step procedure is developed for the half-reduction of lactams to cyclic imines and enamines. N-Nitrosation using dinitrogen tetroxide furnishes N-nitroso lactams, which undergo chemoselective 1,2-reduction to N-nitroso carbinolamines? by one equivalent of hydride delivered from lithium triethylborohydride. The nitroso group is cleaved in a novel way using samarium(II) iodide and dehydration then generates the corresponding imine (which may tautomerise to the isomeric enamine). The reduction can be performed in the presence of esters and has proved efficient for the preparation of 2H-pyrroles (pyrrolenines) and 1H-pyrroles relevant to the study of tetrapyrrole biosynthesis.
View MoreXinji City Taida Sinopec Co., Ltd.
Contact:0086-311-85341278
Address:No.6, Nanhua Road,Xinji City Road,Hebei Province,China
Xi'an yuanfar international trade company
website:https://www.yuanfarchemical.com
Contact:86-029-88745613 ext 828
Address:Floor19th ,B Building, Oak Block,No.36 South Fenghui Road, Dev. Zone of High-Tech Ind.,Xi’an, China
Zibo Linzi Darong Fine Chemical Co., Ltd(expird)
Contact:86-532-67773200; 15689126900
Address:Qidu town,Linzi district,Zibo city,Shandong province,China
Qingdao S. H. Huanyu Imp. & Exp. Co., Ltd.
Contact:86-532-88250866
Address:Room 615, World Trade Centre Building B, Hongkong Middle Roda 6#, Qingdao, Shandong, China
JinTan Pingsheng Chemical Co.,Ltd
Contact:+86-519-82828200
Address:NO.11Danfengxilu Road,Jintan City,Jiangsu,China
Doi:10.1016/0957-4166(95)00204-3
(1995)Doi:10.1080/00397919508011482
(1995)Doi:10.1515/znb-1998-0208
(1998)Doi:10.3390/90400256
(2004)Doi:10.1007/BF00905763
()Doi:10.1021/jm9707479
(1998)
