Propargylation of carbonyl compounds: An efficient method for the synthesis of homopropargyl alcohols

Article abstract of DOI:10.1016/S0040-4039(98)00727-8

Controlled dilithiation of allene, with two equivalents of n- butyllithium, produces the propargyl dianion 5. The latter couples efficiently with carbonyl compounds to produce homopropargyl alcohol in high yields.