Ring formylation of bromobenzoate esters by direct metalation

Article abstract of DOI:10.1080/00397919908085967

A study on the synthesis of a benzaldehyde containing an ester function directly from tert-butyl 4-lithiobenzate was described, t-Butyl 4- bromobenzoate reacted with butyllithium at -78°C in THF, followed by immediate addition of DMF to give the desired benzaldehyde in moderate yield. The scope of this reaction was examined.

Full text of DOI:10.1080/00397919908085967

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic Organic
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Ring Formylation of Bromobenzoate
Esters by Direct Metalation
Andrew S. Kende a & Min Zhong a
a Department of Chemistry , University of Rochester ,
Rochester, NY, 14627
Published online: 17 Sep 2007.
To cite this article: Andrew S. Kende & Min Zhong (1999) Ring Formylation of Bromobenzoate
Esters by Direct Metalation, Synthetic Communications: An International Journal
for Rapid Communication of Synthetic Organic Chemistry, 29:19, 3401-3407, DOI:
10.1080/00397919908085967
To link to this article: http://dx.doi.org/10.1080/00397919908085967
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