Protonic Reorganization and Substrate Structure in Catalysis by Serine Proteases

DOI: 10.1021/ja00531a039

Source and publish data:

Journal of the American Chemical Society p. 3917 - 3922 (1980)

Update date:2022-08-11

Topics:

Authors:

Elrog, James P.

Hogg, John L.

Quinn, Daniel M.

Venkatasubban, K. S.

Schowen, Richard L.

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Article abstract of DOI:10.1021/ja00531a039

Proton inventories (rate measurements in binary mixtures of protium and deuterium oxides) have been used to estimate the number of protons involved in hydrolytic catalysis by serine proteases with various substrates.Trypsin with the oligopeptide analogue

Full text of DOI:10.1021/ja00531a039

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