A Concise Synthesis of (+/-)-Vincadifformine and Related Aspidosperma Alkaloids (+/-)-Desethylvincadifformine, (+/-)-Ibophyllidine, (+/-)-20-Epi-ibophyllidine, and (+/-)-Desethylibophyllidine

DOI: 10.1039/c39850000088

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 88 - 89 (1985)

Update date:2022-08-30

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Authors:

Barsi, Marie-Christine

Das, Bhupesh C.

Fourrey, Jean-Louis

Sundaramoorthi, Rajeswari

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Article abstract of DOI:10.1039/c39850000088

An expeditious total synthesis of (+/-)-vincadifformine (9) and related Aspidosperma alkaloids (+/-)-desethylvincadifformine (10), (+/-)-ibophyllidine (11), (+/-)-20-epi-ibophyllidine (12), and (+/-)-desethylibophyllidine (13) via condensation of a common indole-2-acrylate precursor (2) and an appropriate amine (4) followed by acidic treatment is reported.

Full text of DOI:10.1039/c39850000088

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