Tetrahedron p. 3175 - 3180 (1995)
Update date:2022-08-11
Topics:
Schulz M.
Kluge, R.
Schuessler, M.
Hoffmann, G.
The oxidation of titanium enolates with tert-butylhydroperoxide has been investigated and the main reaction products, the corresponding α-hydroxyketones 7a-f, isolated.The highest diastereoselectivities (>95percent de) were obtained, when titanium enolates of camphor 2d-6d were employed.For comparison, the oxidation of the enolates with dimethyldioxirane is discussed.
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