Synthesis of α,β-Unsaturated Selenoamides by the Condensation Reaction of Lithium Eneselenolate Generated from Selenoacetamide with Aldehydes

Article abstract of DOI:10.1055/s-1997-5781

The reaction of lithium eneselenolate generated from selenoacetamide and LDA with aldehydes gave α,β-unsaturated selenoamides in good to high yields. The successive addition of n-butyllithium and 3-bromo-1-propene to α,β-unsaturated selenoamide 3a gave selenoamide 7 with high selectivity.