Heterocyclic Communications p. 481 - 484 (2006)
Update date:2022-08-11
Topics:
Kiran
Mahadevan
The easy and rapid synthetic procedure for the synthesis of substituted 3-cyanoquinoline derivatives using available laboratory reagents is reported. Vilsmeier-Haack reaction is employed to the p-substituted aniline to yield formyl aniline. These on reaction with cyano ethylacetate and with malono nitrile in presence catalyst results in to 3-substituted quinolines.
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