Enantioselective Oxidation of Thioethers: Synthesis of trans-2-N,N-Dialkylacetamide-1,3-dithiolanes-S-oxide and Their Use in Asymmetric Aldol-Type Reactions

DOI: 10.1016/S0040-4039(00)79595-5

Source and publish data:

Tetrahedron Letters p. 3043 - 3044 (1992)

Update date:2022-08-11

Topics:

Authors:

Corich, Martina

Furia, Fulvio Di

Licini, Giulia

Modena, Giorgio

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)79595-5

(-)-trans-2-N,N-dialkylacetamide-1,3-dithiolanes-S-oxide 2 have been obtained in high d.e. (>99:1) and e.e.(up to 94percent, >98percent after crystallization) by enantioselective oxidation .The aldol-type addition of the magnesium enolate of the N,N-diethyl derivative (-)-2b to iso-butyraldehyde afforded good chemical yields of a single diastereomer.Key Words: Enantioselective oxidation; Asymmetric aldol-type addition, trans-(-)-2-N,N-Diethylacetamide-1,3-dithiolane-S-oxide.

Full text of DOI:10.1016/S0040-4039(00)79595-5

Products guided by the article

Product name:Pyrrolidine, 1-(dichloroacetyl)- (8CI,9CI)

Cas No:20266-01-7

R&D Labs maybe for 20266-01-7

LABTER PARMATECH(BEIJING)CO.,LTD

website:http://www.labter.com.cn/

Contact:+86-10-56330744

Address:NO.19,TIANRONG STREET,DAXING BIOMEDICIAL BASE ,ZHONGGUANCUN SCIENCE AND TECHNOLOGY PARK,BEIJING ,CHINA
Hangzhou Ledun Technology Co.,Ltd.

Contact:86-571-18767088918

Address:No.6 street,XiaSha,Hangzhou,China.
Nantong Auxin Electronic Technology Co., LTD

Contact:86-513-88760026

Address:NO.5-1, Aoxin Road, Haian Hi-tech Development Zone, Jiangsu Province, China
Weifang Ocean Trading Co., Ltd.

Contact:+86-536-2081155

Address:Room2606, Yuqing Building, 518#, Yuquan Road, High-tech Development Zone, Weifang City, Shandong Province, China
Xi'an caijing Opto-Electrical Science & Technology Co., LTD

Contact:+86-29-88294447

Address:NO.168 Zhangba Rd. East, Xi'an, P.R.China

Relevant to this article

Redox-active catalyst based on poly(anilinesulfonic acid)supported gold nanoparticles for aerobic alcohol oxidation in water

Doi:10.1002/adsc.201000451
(2010)
Redox properties of CeO₂at low temperature: The direct synthesis of imines from alcohol and amine

Doi:10.1002/anie.201409601
(2015)
A short enantioselective synthesis of (R)-(+)-γ-jasmolactone

Doi:10.1081/SCC-120039490
(2004)
Release of gas-phase halogens by photolytic generation of OH in frozen halide-nitrate solutions: An active halogen formation mechanism?

Doi:10.1021/jp102072t
(2010)
Fragment-based design of symmetrical bis-benzimidazoles as selective inhibitors of the trimethoprim-resistant, type II R67 dihydrofolate reductase

Doi:10.1021/jm201645r
(2012)
Structurally Characterized Neutral Monoalkyl and -aryl Complexes of Manganese(II)

Doi:10.1021/om030645i
(2004)

Article Doi