Enzymatic synthesis of (S)-(-)-1-(2-thienyl)propyl acetate

Article abstract of DOI:10.1016/0957-4166(95)00284-V

(±)-1-(2-thienyl)propyl acetate was resolved by PCL (Pseudomonas cepacia lipase) catalyzed hydrolysis to afford (S)-(-)-1-(2-thienyl)propyl acetate in >99% e.e. (S)-(-)-1-(2-thienyl)propyl acetate thus obtained was transformed to (S)-(+)-3-octanol, the alarm pheromone of ants, Crematogaster castanea and liengmei.