10.1002/anie.201915456
Angewandte Chemie International Edition
COMMUNICATION
Acknowledgements
Financial support from the Deutsche Forschungsgemeinschaft
(AL 1348/8-1 and INST 186/1237-1) is gratefully acknowledged.
Keywords: Au-catalysis • biaryl synthesis • enantioselective
hydroarylation • cationic ligands • chiral phosphines
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In conclusion,
binaphthalene-2,3’-diols
a
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intramolecular hydroarylation of appropriately designed
alkynones. The use of 3,4-disubstituted imidazolium units
directly attached to the phosphorus atom of the ancillary ligand,
and 2-naphthalenemethyl moieties as protecting group at the
naphthol substrates 2a-t revealed to be essential to achieve high
enantioselectivities. The possibility to transform the 1’-
binaphthalene-2,3’-diols herein described into new chiral
phosphines might inspire the development of new asymmetric
Au-catalyzed transformations. Explorative studies in this
direction are currently in progress in our laboratory.
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