Synthesis of PI(3,4,5)P3 with unsaturated and saturated fatty acid chains

DOI: 10.1016/S0040-4020(99)00551-7

Source and publish data:

Tetrahedron p. 9743 - 9754 (1999)

Update date:2022-08-11

Topics:

Authors:

Watanabe, Yutaka

Nakatomi, Mitsunobu

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Article abstract of DOI:10.1016/S0040-4020(99)00551-7

Synthesis of three PI(3,4,5)P3s, sn-1-O-stearoyl-sn-2-O-arachidonoyl, stearoyl-linolenoyl, and distearoyl phosphatidyl-myo-inositol 3,4,5- trisphosphate with the natural configuration for the arachidonoyl version was established by employing 9-fluorenylmethyl-protected phosphate derivatives.

Full text of DOI:10.1016/S0040-4020(99)00551-7

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