Bioorganic and Medicinal Chemistry Letters p. 195 - 198 (1998)
Update date:2022-08-10
Topics:
Cushman, Mark
Casimiro-Garcia, Agustin
Williamson, Karen
Rice, William G.
A novel alkenyldiarylmethane (ADAM) analog has been synthesized with enhanced potency as an anti-HIV agent. The new compound (ADAM II) inhibits the cytopathic effect of HIV-I(RF) in CEM-SS cells with an EC50 of 13 nM, while it shows cytotoxicit
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