Direct formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D- xylulose 5-phosphate by 1-deoxy-D-xylulose 5-phosphate reductoisomerase, a new enzyme in the non-mevalonate pathway to isopentenyl diphosphate

Article abstract of DOI:10.1016/S0040-4039(98)00802-8

1-Deoxy-D-xylulose 5-phosphate is biotransformed to 2-C-methyl-D- erythritol 4-phosphate in a single step in the presence of NADPH by a new recombinant enzyme named 1-deoxy-D-xylulose 5-phosphate reductoisomerase purified from Escherichia coli.