The Enzyme/Coenzyme/Metal/Substrate Quaternary Complex Generated in the Transition State of the Reduction of Benzoylformate with NAD(P)H Models

Article abstract of DOI:10.1016/0040-4039(95)01298-V

Enantioselectivities in the reduction of methyl benzoylformate with NAD(P)H model compounds, N-α-methylbenzyl-1-propyl-1,4-dihydronicotinamide (PNPH) and N-benzyl-1-propyl-1,4-dihydronicotinamide (PNBH), in the presence of N-protected amino acids have bee