Synthetic Communications p. 3115 - 3127 (1992)
Update date:2022-08-24
Topics:
Langlois
Yang
Soulier
Florac
Robinson-Schopf cyclisation was used to prepare several 1,2,6-trisubstituted-4-piperidones: 1,2,6-trimethyl-4-piperidone, tricyclic ketones 2 and 3 derivatives of coccinelline. In the case of 1,2,6-trimethyl-4-piperidone, a mixture of the trans and cis compounds 4 and 1 was obtained. The pure cis compound was prepared by another route.
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