Total synthesis of methyl picrotoxate via the palladium catalyzed enyne cycloisomerization reaction

DOI: 10.1016/S0040-4020(98)00103-3

Source and publish data:

Tetrahedron p. 3693 - 3704 (1998)

Update date:2022-08-11

Topics:

Authors:

Krische, Michael J.

Trost, Barry M.

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Article abstract of DOI:10.1016/S0040-4020(98)00103-3

Bifurcation of the synthetic pathway affording total syntheses of picrotoxinin, picrotin and corianin from a common synthetic intermediate derived via the palladium catalyzed enyne cycloisomerization leads to the total synthesis of the picrotoxane sesquiterpene methyl picrotoxate.

Full text of DOI:10.1016/S0040-4020(98)00103-3

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