Conformational analysis of 9-substituted adenines in relation to their microsomal N1-oxidation

Article abstract of DOI:10.1111/j.2042-7158.1989.tb06480.x

Metabolic N-oxidation of adenine, 9-methyladenine, 9-benzyladenine, 9-benzhydryladenine and 9-trityladenine has been investigated using hepatic microsomes from hamster, guinea-pig, rabbit, mouse, rat, and dog. N¹-Oxide formation occurs with 9-b