Action of nitrile hydratase from Rhodococcus rhodochrous IFO 15564 on derivatives of 2,5-anhydro-D-allononitrile

Article abstract of DOI:10.1271/bbb.60.1540

The conversion of 2,5-anhydro-D-allononitrile derivatives by a nitrile hydratase from Rhodococcus rhodochrous IFO 15564 was studied. The activity of the enzyme was strongly effected by the steric bulkiness of the substituents at the 3-position of the substrates, and the corresponding amides were obtained in high yields from the nitriles with free hydroxyl groups at the 3- and 4-positions.

Full text of DOI:10.1271/bbb.60.1540

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Action of Nitrile Hydratase from Rhodococcus
rhodochrous IFO 15564 on Derivatives of 2,5-
Anhydro-d-allononitrile
Masahiro Yokoyamaa, Yuko Nakatsukaa, Takeshi Sugaia & Hiromichi Ohtaa
a Department of Chemistry, Keio University, 3–14–1 Hiyoshi, Kohoku-ku, Yokohama 223,
Japan
Published online: 12 Jun 2014.
To cite this article: Masahiro Yokoyama, Yuko Nakatsuka, Takeshi Sugai & Hiromichi Ohta (1996) Action of Nitrile
Hydratase from Rhodococcus rhodochrous IFO 15564 on Derivatives of 2,5-Anhydro-d-allononitrile, Bioscience,
Biotechnology, and Biochemistry, 60:9, 1540-1542, DOI: 10.1271/bbb.60.1540
To link to this article: http://dx.doi.org/10.1271/bbb.60.1540
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