Expression, and Developmental Regulation. Proceedings of the National Academy of Sciences of
the United States of America 83, 5779‐5783
16.
17.
18.
19.
20.
Vogel, S., Mendelsohn, C. L., Mertz, J. R., Piantedosi, R., Waldburger, C., Gottesman, M. E., and
Blaner, W. S. (2001) Characterization of a new member of the fatty acid‐binding protein family
that binds all‐trans‐retinol. The Journal of biological chemistry 276, 1353‐1360
MacDonald, P. N., and Ong, D. E. (1987) Binding specificities of cellular retinol‐binding protein
and cellular retinol‐binding protein, type II. The Journal of biological chemistry 262, 10550‐
10556
Levin, M. S., Locke, B., Yang, N. C., Li, E., and Gordon, J. I. (1988) Comparison of the ligand
binding properties of two homologous rat apocellular retinol‐binding proteins expressed in
Escherichia coli. The Journal of biological chemistry 263, 17715‐17723
Kawaguchi, R., Yu, J., Ter‐Stepanian, M., Zhong, M., Cheng, G., Yuan, Q., Jin, M., Travis, G. H.,
Ong, D., and Sun, H. (2011) Receptor‐mediated cellular uptake mechanism that couples to
intracellular storage. ACS chemical biology 6, 1041‐1051
Kawaguchi, R., Yu, J., Honda, J., Hu, J., Whitelegge, J., Ping, P., Wiita, P., Bok, D., and Sun, H.
(2007) A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A.
Science 315, 820‐825
21.
22.
Herr, F. M., and Ong, D. E. (1992) Differential interaction of lecithin‐retinol acyltransferase with
cellular retinol binding proteins. Biochemistry 31, 6748‐6755
Ghyselinck, N. B., Bavik, C., Sapin, V., Mark, M., Bonnier, D., Hindelang, C., Dierich, A., Nilsson, C.
B., Hakansson, H., Sauvant, P., Azais‐Braesco, V., Frasson, M., Picaud, S., and Chambon, P. (1999)
Cellular retinol‐binding protein I is essential for vitamin A homeostasis. The EMBO journal 18,
4903‐4914
23.
24.
Saari, J. C., Nawrot, M., Garwin, G. G., Kennedy, M. J., Hurley, J. B., Ghyselinck, N. B., and
Chambon, P. (2002) Analysis of the visual cycle in cellular retinol‐binding protein type I (CRBPI)
knockout mice. Investigative ophthalmology & visual science 43, 1730‐1735
Golczak, M., Kuksa, V., Maeda, T., Moise, A. R., and Palczewski, K. (2005) Positively charged
retinoids are potent and selective inhibitors of the trans‐cis isomerization in the retinoid (visual)
cycle. Proceedings of the National Academy of Sciences of the United States of America 102,
8162‐8167
25.
26.
Maeda, A., Maeda, T., Golczak, M., and Palczewski, K. (2008) Retinopathy in mice induced by
disrupted all‐trans‐retinal clearance. The Journal of biological chemistry 283, 26684‐26693
Zhang, J., Dong, Z., Mundla, S. R., Hu, X. E., Seibel, W., Papoian, R., Palczewski, K., and Golczak,
M. (2015) Expansion of first‐in‐class drug candidates that sequester toxic all‐trans‐retinal and
prevent light‐induced retinal degeneration. Molecular pharmacology 87, 477‐491
Golczak, M., Imanishi, Y., Kuksa, V., Maeda, T., Kubota, R., and Palczewski, K. (2005)
Lecithin:retinol acyltransferase is responsible for amidation of retinylamine, a potent inhibitor of
the retinoid cycle. The Journal of biological chemistry 280, 42263‐42273
27.
28.
29.
Golczak, M., Sears, A. E., Kiser, P. D., and Palczewski, K. (2015) LRAT‐specific domain facilitates
vitamin A metabolism by domain swapping in HRASLS3. Nature chemical biology 11, 26‐32
Maeda, A., Maeda, T., Golczak, M., Imanishi, Y., Leahy, P., Kubota, R., and Palczewski, K. (2006)
Effects of potent inhibitors of the retinoid cycle on visual function and photoreceptor protection
from light damage in mice. Molecular pharmacology 70, 1220‐1229
30.
Sacchettini, J. C., Gordon, J. I., and Banaszak, L. J. (1989) Crystal structure of rat intestinal fatty‐
acid‐binding protein. Refinement and analysis of the Escherichia coli‐derived protein with bound
palmitate. Journal of molecular biology 208, 327‐339
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