CONJUGATE ADDITIONS TO α,β-UNSATURATED CARBONYL COMPOUNDS IN AQUEOUS MEDIA

Article abstract of DOI:10.1016/S0040-4039(00)84739-5

Alkyl halides in the presence of zinc copper couple add smoothly to α-enones and α-enals in aqueous solvents.Sonication enhances the efficiency of the process, which leads to the conjugate adducts in high yields.The reaction follows most probably a radical pathway, and can be used for the addition of functionalized groups.