Tetrahedron Letters p. 3149 - 3152 (1986)
Update date:2022-08-11
Topics:
Petrier, C.
Dupuy, C.
Luche, J. L.
Alkyl halides in the presence of zinc copper couple add smoothly to α-enones and α-enals in aqueous solvents.Sonication enhances the efficiency of the process, which leads to the conjugate adducts in high yields.The reaction follows most probably a radical pathway, and can be used for the addition of functionalized groups.
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