
Helvetica Chimica Acta p. 51 - 58 (1994)
Update date:2022-08-31
Topics:
Mancini
Guella
Debitus
Pietra
A series of ceramides, called oceanapins A-F, which are unique for branching at both the sphingosine and fatty-acid chains, have been isolated as pure compounds from the haplosclerid sponge Oceanapia cf. tenuis of the Coral Sea. Following acid hydrolysis, both the fatty-acid and the sphingosine portions were obtained separately, which allowed their unequivocal structural definition. The absolute configuration was secured via protection of C(l')-OH and Mosher's esterification at C(3')-OH of the oceanapins.
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