Triflamides for protection and cyclization of tetraamines to tetraazamacrocycles

DOI: 10.1016/S0040-4039(00)61129-2

Source and publish data:

Tetrahedron Letters p. 5505 - 5508 (1992)

Update date:2022-08-11

Topics:

Authors:

Panetta Panetta

Yaouanc Yaouanc

Handel Handel

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Article abstract of DOI:10.1016/S0040-4039(00)61129-2

A facile two-step synthesis of tetraazamacrocycles is reported starting from trifluoromethanesulfonyl derivatives of linear tetraamines. After cyclization, the macrocycle was deprotected using sodium in liquid ammonia.

Full text of DOI:10.1016/S0040-4039(00)61129-2

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