Synthesis of 5- and 6-oxoalkanoic acids by copper(II) catalyzed oxidative cleavage of cycloalkanones with dioxygen

Article abstract of DOI:10.1055/s-1993-25801

α-Substituted cycloalkanones are oxidized to oxo acids by the copper(II)/dioxygen/acetic acid/water system. This catalytic procedure compares well with the previously described systems involving vanadium precursors.