Synthesis of 4'-thio-β-D-arabinofuranosylcytosine (4'-thio-ara-C) and comparison of its anticancer activity with that of ara-C

Article abstract of DOI:10.1080/15257770008033012

4'-thio-β-D-arabinofuranosylcytosine was synthesized by a facile route in high yields. It was evaluated for antitumor activity against a panel of human tumors, both in vitro and in vivo.

Full text of DOI:10.1080/15257770008033012

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Nucleosides, Nucleotides and Nucleic
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Synthesis of 4′-Thio-β-D-
arabinofuranosylcytosine (4′-Thio-ara-
C) and Comparison of Its Anticancer
Activity with That of Ara-C
Kamal N. Tiwari a , Anita T. Shortnacy-fowler a , Loredana
Cappellacci a , William B. Parker a , William R. Waud a , John A.
Montgomery a & John A. Secrist III a
a Southern Research Institute , P. O. Box 55305, Birmingham,
Alabama, 35255-5305
Published online: 24 Sep 2006.
To cite this article: Kamal N. Tiwari , Anita T. Shortnacy-fowler , Loredana Cappellacci , William B.
Parker , William R. Waud , John A. Montgomery & John A. Secrist III (2000) Synthesis of 4′-Thio-β-D-
arabinofuranosylcytosine (4′-Thio-ara-C) and Comparison of Its Anticancer Activity with That of Ara-C,
Nucleosides, Nucleotides and Nucleic Acids, 19:1-2, 329-340, DOI: 10.1080/15257770008033012
To link to this article: http://dx.doi.org/10.1080/15257770008033012
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