Stereochemical probes for the estrogen receptor: Synthesis and receptor binding of (17α,20E/Z)-21-phenyl-19-norpregna-1,3,5(10),20-tetraene-3,17β- diols

DOI: 10.1016/S0039-128X(96)00201-2

Source and publish data:

Steroids p. 718 - 722 (1996)

Update date:2022-08-29

Topics:

Authors:

Hanson, Robert N.

Herman, Lee W.

Fiaschi, Rita

Napolitano, Elio

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Article abstract of DOI:10.1016/S0039-128X(96)00201-2

Previous studies from our laboratory using 17α-E and 17α-Z-halovinyl and phenylthiovinyl estradiols demonstrated a marked preference for the Z stereochemistry and a significant steric tolerance for the Z-vinyl substituent. To further explore the extent of

Full text of DOI:10.1016/S0039-128X(96)00201-2

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Product name:3,17β-dihydroxy-17α-(2'-phenyl-1'-ethyn-1'-yl)estra-1,3,5(10)-triene

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