
Tetrahedron Letters p. 3419 - 3422 (1999)
Update date:2022-08-11
Topics:
Chou, Wen-Chih
Chou, Ming-Chen
Lu, Yann-Yu
Chen, Shyh-Fong
A number of N-acylalkylenediamines were synthesized in high yields by in situ monoamidation of carboxylic acids with diamines. The amidation reactions were carried out simply by heating the substrates at 110 °C for 5-24 h in the presence of HMDS.
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Doi:10.1021/jo00908a025
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(1993)