Tetrahedron p. 8841 - 8846 (1998)
Update date:2022-08-11
Topics:
Aresta, Michele
Quaranta, Eugenio
Liberio, Roberto
Dileo, Caterina
Tommasi, Immacolata
4-OH benzoic acid has been synthesized from phenol and CO2 at room temperature and sub-atmospheric pressure of CO2 with 100% selectivity, using a Carboxylase enzyme. A cheap, fast and easy method for the phosphorylation of phenol has been also developed. This represents the first biotechnological application of a Carboxylase enzyme.
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