Reaction of 2-amino-2-cycloalken-1-one derivatives with p-benzoquinones, III

Article abstract of DOI:10.1002/ardp.19933260708

Reaction of 1 with 2a yields the spirocyclic benzoxazine 3a, by-product is a 2,3-bisadduct 4. Quinone 6 is isolated from the reaction of 1b with 2b. 8 and 9a react to yield the benzofurane 11, which is acetylated to the hydroquinone derivative 14 and transformed to 13, respectively. Reaction of 8 with 9b yields 7a. 16a,b are obtained from 8 or 1 with 15. 16a is acetylated to 16c and split into 17a.