Synthesis and in vitro study of platelet antiaggregant activity of 2(4)-imidazol-1-yl-4(2)-cycloalkylamino pyrimidines

DOI: 10.1016/0223-5234(91)90123-5

Source and publish data:

European Journal of Medicinal Chemistry p. 729 - 733 (1991)

Update date:2022-08-31

Topics:

Authors:

Del Corona

Signorelli

Manzardo

Pinzetta

Coppi Coppi

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Article abstract of DOI:10.1016/0223-5234(91)90123-5

The synthesis of some 2(4)-imidazol-1-yl-4(2)-cycloalkylaminopyrimidines are reported. The compounds demonstrated a marked antiaggregating activity superior to dipyridamole, ASA, ticlopidine and similar to that of indobufen.

Full text of DOI:10.1016/0223-5234(91)90123-5

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