Tetrahedron Letters p. 2987 - 2988 (1984)
Update date:2022-08-17
Topics:
Sakai, Takashi
Ito, Hiroshi
Yamawaki, Akitoshi
Takeda, Akira
Acylation of 3-methyl-2,3-bis(trimethylsiloxy)-1-butene (PhLi) with (E)-2-methyl-2-butenoyl chloride gives the corresponding 3(2H)-furanone derivative, which can be readily converted to the naturally occurring antitumor agent Geiparvarin by two steps.
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Doi:10.1039/j29680000408
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