European Journal of Medicinal Chemistry p. 479 - 486 (1994)
Update date:2022-08-10
Topics:
Bonsignore, L.
Logu, A. de
Loy, G.
Lavagna, S.M.
Secci, D.
Some semisynthetic penicillins 6-substituted with benzo-condensed heterocyclic derivatives were prepared using the reaction of carbon suboxide with Schiff bases and disubstituted benzoic acids.The microbiological assay performed with the penicillins and their intermediates showed a good activity for one Schiff base and a weak activity for the other compounds. coumarin penicillin / Schiff base / carbon suboxide / antimicrobial activity
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