Steroids p. 123 - 136 (1983)
Update date:2022-08-18
Topics:
Klingler
Haupt
Postel
Knuppen
6-Oxoestriol-6-(O-carboxymethyl)oxime-aminobutylethyl-isoluminol conjugate was synthesized. This luminogenic estriol derivative enabled us to develop a solid phase immunoassay method for the determination of unconjugated estriol in serum of pregnant women by the measurement of the bound estriol-isoluminol conjugate upon oxidation with a hydrogen peroxide/microperoxidase system. The sensitivity of the assay was 700 pmol/l. Results obtained by radioimmunoassay and the described method showed good agreement (r = 0.95). The chemiluminescent method is applicable in the routine measurement of unconjugated estriol.
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(2020)Doi:10.1248/cpb.40.3142
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(2009)Doi:10.1002/jhet.724
(2012)Doi:10.1007/BF00564844
()Doi:10.1016/S0040-4039(03)00032-7
(2003)
