Practical synthesis of Ambrox from farnesyl acetate involving lipase catalyzed resolution

DOI: 10.1016/0957-4166(96)00203-0

Source and publish data:

Tetrahedron Asymmetry p. 1695 - 1704 (1996)

Update date:2022-08-11

Topics:

Authors:

Tanimoto, Hisahide

Oritani, Takayuki

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Article abstract of DOI:10.1016/0957-4166(96)00203-0

Enantiomerically pure Ambrox was synthesized from (-)-13,14,15,16- tetranor-8α,12-labdanediol, which was prepared by lipase catalyzed kinetic resolution of (±)-drimane-8,11-diol.

Full text of DOI:10.1016/0957-4166(96)00203-0

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Product name:1-Naphthaleneethanol,decahydro-2-hydroxy- 2,5,5,8a-tetramethyl-,(1R,2R,4aS,8aS)-

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