Synthesis of (-)-Methyl Shikimate via Enzymatic Resolution of (1S*, 4R*, 5R*)-4-Hydroxy-6-oxabicyclo[3.2.1]oct-2-en-7-one

Article abstract of DOI:10.1271/bbb.65.2106

The synthesis of methyl (-)-shikimate [(-)-2] was achieved via lipase-catalyzed optical resolution of (1S*, 4R*, 5R*)-4-hydroxy-6-oxabicyclo[3.2.1]oct-2-en-7-one (3). Transesterification of (±)-3 and vinyl acetate with lipase MY and subsequent hydrolysis

Full text of DOI:10.1271/bbb.65.2106

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Synthesis of (-)-Methyl Shikimate via Enzymatic
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Resolution of (1S , 4R , 5R )-4-Hydroxy-6-
oxabicyclo[3.2.1]oct-2-en-7-one
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Takayuki ORITANI , Rumi UEDA & Hiromasa KIYOTA
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Laboratory of Applied Bioorganic Chemistry, Division of Life Science, Graduate School
of Agricultural Science, Tohoku University
Published online: 22 May 2014.
To cite this article: Takayuki ORITANI, Rumi UEDA & Hiromasa KIYOTA (2001) Synthesis of (-)-Methyl Shikimate via
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Enzymatic Resolution of (1S , 4R , 5R )-4-Hydroxy-6-oxabicyclo[3.2.1]oct-2-en-7-one, Bioscience, Biotechnology, and
Biochemistry, 65:9, 2106-2109, DOI: 10.1271/bbb.65.2106
To link to this article: http://dx.doi.org/10.1271/bbb.65.2106
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