An alternative synthesis of 2-chloro-5-hydroxypyridine: A key component of the non-opioid analgesic agent ABT-594

Article abstract of DOI:10.1080/00397910008087025

The synthesis of the biologically useful synthon 2-chloro-5-hydroxypyridine from 3-iodo-6-chloropyridine is described.

Full text of DOI:10.1080/00397910008087025

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Synthetic Communications: An
International Journal for Rapid
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Organic Chemistry
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An Alternative Synthesis of
2-Chloro-5-Hydroxypyridine:
A Key Component of the
Non-Opioid Analgesic Agent
ABT-594
Grant R. Krow a , Yushi Xiao a , Kevin Cannon a , Scot
A. Swan a & Andrew Nickel a
a Department of Chemistry , Temple University ,
Philadelphia, PA, 19122
Published online: 04 Dec 2007.
To cite this article: Grant R. Krow , Yushi Xiao , Kevin Cannon , Scot A. Swan &
Andrew Nickel (2000) An Alternative Synthesis of 2-Chloro-5-Hydroxypyridine: A Key
Component of the Non-Opioid Analgesic Agent ABT-594, Synthetic Communications:
An International Journal for Rapid Communication of Synthetic Organic Chemistry,
30:22, 4093-4096, DOI: 10.1080/00397910008087025
To link to this article: http://dx.doi.org/10.1080/00397910008087025
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