Asymmetric synthesis of α-amino phosphonic acids employing versatile sulfinimines and sulfonimines

Article abstract of DOI:10.1080/10426509908546265

The addition of metallophosphites to activated imino substrates such as sulfonimine 1 and sulfinimines 4 was successfully achieved. High diastereoselectivities and good yields were obtained with sulfinimine acceptors. The nucleophilic addition was applied to the development of a new methodology for the synthesis of enantiomerically homogeneous α-amino phosphonic acids.

Full text of DOI:10.1080/10426509908546265

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Phosphorus, Sulfur, and
Silicon and the Related
Elements
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Asymmetric Synthesis
of α-Amino Phosphonic
Acids Employing
Versatile Sulfinimines
and Sulfonimines
Isabelle M. Lefebvre & Slayton A. Evans
a Chemistry Department , The University
of North Carolina at Chapel Hill , North
Carolina 27599–3290, USA
b Chemistry Department , The University
of North Carolina at Chapel Hill , North
Carolina 27599–3290, USA
Published online: 17 Mar 2008.
To cite this article: Isabelle M. Lefebvre & Slayton A. Evans (1999)
Asymmetric Synthesis of α-Amino Phosphonic Acids Employing Versatile
Sulfinimines and Sulfonimines, Phosphorus, Sulfur, and Silicon and the
Related Elements, 144:1, 397-400, DOI: 10.1080/10426509908546265
To link to this article: http://dx.doi.org/10.1080/10426509908546265
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